BDBM16307 2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carboximidamide::2-(pyridin-2-ylmethyl)-1H-benzimidazole-6-carboximidamide::APD-5::CHEMBL204126

SMILES NC(=N)c1ccc2nc(Cc3ccccn3)[nH]c2c1

InChI Key InChIKey=MHSMXTLGYPLSJM-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16307   

TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16307(2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...)
Affinity DataKi:  310nM ΔG°:  -8.78kcal/molepH: 8.2 T: 2°CAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Arris

LigandPNGBDBM16307(2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carbo...)
Affinity DataKi:  3.58E+5nMAssay Description:Enzymes were incubated with inhibitors at eight inhibitor concentrations bracketing the Ki, prepared by serial dilution along with control lacking th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed